4-Methoxycyclohexanol (cis,trans) → 4-Methoxycyclohexanone
反応式
[CH3:1][O:2][CH:3]1[CH2:8][CH2:7][CH:6]([OH:9])[CH2:5][CH2:4]1.[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl>[CH3:1][O:2][CH:3]1[CH2:8][CH2:7][C:6](=[O:9])[CH2:5][CH2:4]1参加物
4
実験手順
4-Methoxycyclohexanol (2.0 g, 15.0 mmol) was taken up in 150 mL of DCM. Pyridinium chlorochromate (5.0 g, 23.0 mmol) was added. After 60 hours, the mixture was filtered through a plug of Florisil and concentrated under reduced pressure. The residue was taken up in 50 mL of ether and filtered through a plug of silica gel. The solvent was removed under reduced pressure, affording 4-methoxycyclohexanone as a light yellow oil.
後処理
- filtrationthe mixture was filtered through a plug of Florisil
- concentrationconcentrated under reduced pressure
- filtrationfiltered through a plug of silica gel
- customThe solvent was removed under reduced pressure
出典と根拠
- ORDレコード
- ord-f507dd16125c411db6001cdd6e80706a
- 出典データセット
- uspto-grants-2011_11
- 特許番号
- US08053438B2
反応ノート
読み込み中…