Aluminum(III) Chloride → 1-(4-Chloro-2-hydroxyphenyl)ethanone
反応式
[OH:1][C:2]1[CH:7]=[C:6](OC(C(OCC)=O)(C)C)[CH:5]=[CH:4][C:3]=1[C:17](=[O:19])[CH3:18].[Cl-:20].[Al+3].[Cl-].[Cl-]>>[Cl:20][C:6]1[CH:5]=[CH:4][C:3]([C:17](=[O:19])[CH3:18])=[C:2]([OH:1])[CH:7]=1参加物
3
反応条件
- 温度
- 200 °C
実験手順
3-chlorophenyl acetate (starting material 2) was mixed with aluminium chloride (3 eq). The mixture was heated at 200° C. for 1 hour. The reaction medium was cooled to room temperature then poured in ice. The aqueous phase was extracted with methylene chloride which was dried on magnesium sulfate then vacuum evaporated.
後処理
- temperatureThe reaction medium was cooled to room temperature
- additionthen poured in ice
- extractionThe aqueous phase was extracted with methylene chloride which
- customwas dried on magnesium sulfate
- customvacuum evaporated
出典と根拠
- ORDレコード
- ord-5c461b7df70d40b1a5e16f14447e9a27
- 出典データセット
- uspto-grants-2011_11
- 特許番号
- US08058308B2
反応ノート
読み込み中…