Hydroxylamine → N'-hydroxyoctanimidamide

HRID 557990ノート

反応式

HRID 557990 の反応式
[C:1](#[N:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[NH2:10][OH:11].O>CCO>[OH:11][N:10]=[C:1]([NH2:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

参加物

5

反応物 3

HCID 787HydroxylamineHCID 962WaterHCID 31286Octanenitrile

生成物 1

HCID 3661326N'-hydroxyoctanimidamide収率 74.6%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Octanonitrile (1 g, 7.99 mmol) and hydroxylamine (50% in water, 0.74 cm3, 0.79 g, 12 mmol, 1.5 eq) in EtOH (1 cm3) were stirred at room temperature for 7 days. Water (10 cm3) was then added. This caused crystals to precipitate, these were collected by filtration and dried in high vacuum line to give the product N′-hydroxyoctanimidamide (0.94 g, 74.6%) as a white solid, mp 73-75° C.

後処理

  1. customThis caused crystals to precipitate
  2. filtrationthese were collected by filtration
  3. customdried in high vacuum line

出典と根拠

ORDレコード
ord-c52d23a46d9f4c978b0f76e8f9097f91
出典データセット
uspto-grants-2011_11
特許番号
US08062429B2

反応ノート

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