Hydroxylamine → HCID 74313832、化合物
反応式
[CH2:1]([O:3][CH2:4][CH2:5][O:6][CH2:7][CH2:8][C:9]#[N:10])[CH3:2].[NH2:11][OH:12]>CCO>[CH2:1]([O:3][CH2:4][CH2:5][O:6][CH2:7][CH2:8][C:9](=[N:11][OH:12])[NH2:10])[CH3:2]参加物
4
実験手順
A solution of 3-(2-ethoxyethoxy)propanenitrile (1 g, 7 mmol) and NH2OH (50% in water, 0.64 cm3, 10.5 mmol) in EtOH (10 cm3) were heated to reflux for 24 hours, after which the solvent and excess hydroxylamine were removed by rotary evaporator. The residue was freeze-dried and kept in high vacuum line for several hours to give 3-(2-ethoxyethoxy)-N′-hydroxypropanimidamide (1.2 g, 97.6%) as a colorless oil.
後処理
- temperatureto reflux for 24 hours
- customafter which the solvent and excess hydroxylamine were removed by rotary evaporator
- customThe residue was freeze-dried
- waitkept in high vacuum line for several hours
出典と根拠
- ORDレコード
- ord-1bf948689b924eab95645684fa0c0d3d
- 出典データセット
- uspto-grants-2011_11
- 特許番号
- US08062429B2
反応ノート
読み込み中…