化工社化工社 化学情報印刷レポート · 研究参考用
Water → Triphenylsulfonium 2-pivaloyloxy-1,1-difluoroethanesulfonate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Triphenylsulfonium iodide | HCID 21881071 | — |
| 反応物 | Sodium 2-pivaloyloxy-1,1-difluoroethanesulfonate | HCID 57817346 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Triphenylsulfonium 2-pivaloyloxy-1,1-difluoroethanesulfonate | HCID 86632753 | 95% |
反応手順
In 700 g of dichloromethane and 400 g of water were dissolved 159 g (0.37 mol) of sodium 2-(pivaloyloxy)-1,1-difluoroethanesulfonate (purity 63%) and 132 g (0.34 mol) of triphenylsulfonium iodide. The organic layer was separated, washed three times with 200 g of water, and concentrated. Diethyl ether was added to the concentrate for recrystallization, obtaining the target compound as white crystals. 164 g (yield 95%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08062828B2 |
| 出典データセット | uspto-grants-2011_11 |
| ORD ID | ord-b96e0558340a40b39c7c5b2e0458e54b |
| 出典メモ | uspto-grants-2011_11 |