3-(1H-Pyrazol-3-yl)aniline → 4-(3-(1H-pyrazol-5-yl)phenylamino)-2-((1R,2S)-2-aminocyclohexylamino)pyrimidine-5-carboxamide

HRID 559021

反応式

HRID 559021 の反応式
[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13]([NH:15][C:16]2[CH:21]=[CH:20][C:19](C3ON=CC=3)=[CH:18][CH:17]=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1.[NH:30]1[C:34](C2C=C(C=CC=2)N)=[CH:33][CH:32]=[N:31]1>>[NH:30]1[C:34]([C:18]2[CH:17]=[C:16]([NH:15][C:13]3[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=[C:9]([NH:8][C@@H:3]4[CH2:4][CH2:5][CH2:6][CH2:7][C@@H:2]4[NH2:1])[N:14]=3)[CH:21]=[CH:20][CH:19]=2)=[CH:33][CH:32]=[N:31]1

参加物

3

反応物 2

HCID 27353983-(1H-Pyrazol-3-yl)anilineHCID 461846122-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[4-(1,2-oxazol-5-yl)anilino]pyrimidine-5-carboxamide

生成物 1

HCID 461843694-(3-(1H-pyrazol-5-yl)phenylamino)-2-((1R,2S)-2-aminocyclohexylamino)pyrimidine-5-carboxamide

実験手順

This compound was synthesised using the synthetic scheme described for the synthesis of compound 122, and using 3-(1H-pyrazol-5-yl)aniline in step 1. MS: 393.0 (M+H).

後処理

  1. customThis compound was synthesised

出典と根拠

ORDレコード
ord-c87e3c69ed314b2aba537e79f3de1f5b
出典データセット
uspto-grants-2011_11
特許番号
US08063058B2

関連ノート

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