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ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)acetate → 1-[3-(2,4-Dichlorophenyl)-1,9-dimethyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indol-6-yl]-4-(tetrahydropyran-2-yloxy)butane-1,3-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)acetate | HCID 10899396 | — |
| 反応物 | 6-acetyl-3-(2,4-dichlorophenyl)-1,9-dimethyl-1,9-dihydro-2H-pyrido[2,3-b]indol-2-one | HCID 66997309 | — |
| 生成物 | 1-[3-(2,4-Dichlorophenyl)-1,9-dimethyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indol-6-yl]-4-(tetrahydropyran-2-yloxy)butane-1,3-dione | HCID 66997467 | — |
反応手順
The process is carried out as in Example 80 above, with the compound from preparation 1.10E, 6-acetyl-3-(2,4-dichlorophenyl)-1,9-dimethyl-1,9-dihydro-2H-pyrido[2,3-b]indol-2-one and (tetrahydropyran-2-yloxy)acetic acid ethyl ester.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08063061B2 |
| 出典データセット | uspto-grants-2011_11 |
| ORD ID | ord-4298017115e34b7d840cf9b7628d816f |
| 出典メモ | uspto-grants-2011_11 |