化工社化工社 化学情報印刷レポート · 研究参考用
1,3-Dimethyl-5-nitroisoquinoline → 1,3-Dimethylisoquinolin-5-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,3-Dimethyl-5-nitroisoquinoline | HCID 57456780 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 1,3-Dimethylisoquinolin-5-amine | HCID 22337624 | — |
反応手順
A solution of D3 (2.01 g, 9.94 mM) and 10% palladium on charcoal (1 g) in methanol was hydrogenated at atmospheric pressure for 1 h. The catalyst was filtered off and the filtrate concentrated under reduced pressure to afford the title compound as an off white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08063078B2 |
| 出典データセット | uspto-grants-2011_11 |
| ORD ID | ord-8b298f91f862430fb1b4d0d9f7fe359c |
| 出典メモ | uspto-grants-2011_11 |