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HRID 560433作成日：2026年10月25日

1-Ethyl-3-methyl-1H-pyrazole-5-carboxylic acid → 2-Ethyl-5-methyl-2h-pyrazole-3-carboxylic acid{(1s,2s,5r)-3-[5-(3-chloro-phenyl)-2-methyl-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide

https://huagongshe.com/reaction/560433

反応式

関与物質

役割名称HCID仕込み量
反応物1-Ethyl-3-methyl-1H-pyrazole-5-carboxylic acidHCID 2743794—
反応物((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-[5-(3-chloro-phenyl)-2-methyl-thiazol-4-yl]-methanoneHCID 66998493—
生成物2-Ethyl-5-methyl-2h-pyrazole-3-carboxylic acid{(1s,2s,5r)-3-[5-(3-chloro-phenyl)-2-methyl-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amideHCID 25182106—

反応手順

prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-[5-(3-chloro-phenyl)-2-methyl-thiazol-4-yl]-methanone with 2-Ethyl-5-methyl-2H-pyrazole-3-carboxylic acid. LC-MS (basic): tR=0.89 min; [M+H]+=484.3.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08063099B2
出典データセットuspto-grants-2011_11
ORD IDord-03ff6d2a37fd463687d68a11d0ec3745
出典メモuspto-grants-2011_11