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HRID 560477作成日：2026年10月25日

3-Methylimidazo[2,1-b]thiazole-2-carboxylic acid → 3-Methyl-imidazo[2,1-b]thiazole-2-carboxylic acid{(1s,2s,5r)-3-[2-amino-5-(3-fluoro-phenyl)-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide

https://huagongshe.com/reaction/560477

反応式

関与物質

役割名称HCID仕込み量
反応物3-Methylimidazo[2,1-b]thiazole-2-carboxylic acidHCID 56965725—
反応物[2-Amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,2S,5R)-2-aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-methanoneHCID 86644211—
生成物3-Methyl-imidazo[2,1-b]thiazole-2-carboxylic acid{(1s,2s,5r)-3-[2-amino-5-(3-fluoro-phenyl)-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amideHCID 87229795—

反応手順

prepared by reaction of [2-Amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,2S,5R)-2-aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-methanone with 3-Methyl-imidazo[2,1-b]thiazole-2-carboxylic acid. LC-MS (basic): tR=0.73 min; [M+H]+=497.3.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08063099B2
出典データセットuspto-grants-2011_11
ORD IDord-a7c8a2fd6b9c4c8cbab093ce6af08ad5
出典メモuspto-grants-2011_11