4-Chlorobenzaldehyde → (4-Chlorophenyl)(4-fluorophenyl)methanol

HRID 561419

反応式

HRID 561419 の反応式
Br[C:2]1[CH:7]=[CH:6][C:5]([F:8])=[CH:4][CH:3]=1.[Cl:9][C:10]1[CH:17]=[CH:16][C:13]([CH:14]=[O:15])=[CH:12][CH:11]=1.FC1C=CC(C(C2C=CC(C(F)(F)F)=CC=2)O)=CC=1>>[Cl:9][C:10]1[CH:17]=[CH:16][C:13]([CH:14]([C:2]2[CH:7]=[CH:6][C:5]([F:8])=[CH:4][CH:3]=2)[OH:15])=[CH:12][CH:11]=1

参加物

4

反応物 3

HCID 77264-ChlorobenzaldehydeHCID 99931-Bromo-4-fluorobenzeneHCID 579773alpha-(4-Fluorophenyl)-4-(trifluoromethyl)benzenemethanol

生成物 1

HCID 12634874(4-Chlorophenyl)(4-fluorophenyl)methanol

実験手順

The title compound was prepared starting from 6.00 g (34.29 mmol) of 4-bromofluorobenzene and 5.78 g (41.14 mmol) of 4-chlorobenzaldehyde in analogy to the synthesis of the compound from Example 80A. 7.14 g (88% of theory) of the title compound were obtained.

後処理

  1. customThe title compound was prepared

出典と根拠

ORDレコード
ord-7b4bb04677dc490c944a5f29082de05f
出典データセット
uspto-grants-2011_11
特許番号
US08063234B2

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