化工社化工社 化学情報印刷レポート · 研究参考用
1-Bromo-4-fluorobenzene → (2,4-Difluorophenyl)(4-fluorophenyl)methanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Bromo-4-fluorobenzene | HCID 9993 | — |
| 反応物 | 2,4-Difluorobenzaldehyde | HCID 73770 | — |
| 反応物 | alpha-(4-Fluorophenyl)-4-(trifluoromethyl)benzenemethanol | HCID 579773 | — |
| 生成物 | (2,4-Difluorophenyl)(4-fluorophenyl)methanol | HCID 58392299 | — |
反応手順
The title compound was prepared starting from 1.00 g (5.71 mmol) of 4-bromofluorobenzene and 0.97 g (6.86 mmol) of 2,4-difluorobenzaldehyde in analogy to the synthesis of the compound from Example 80A. 0.53 g (38% of theory) of the title compound was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08063234B2 |
| 出典データセット | uspto-grants-2011_11 |
| ORD ID | ord-57da85f590af46a59a7aa327c3936dca |
| 出典メモ | uspto-grants-2011_11 |