化工社化工社 化学情報印刷レポート · 研究参考用
1-Bromo-4-fluorobenzene → (4-Chloro-2-fluorophenyl)(4-fluorophenyl)methanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Bromo-4-fluorobenzene | HCID 9993 | — |
| 反応物 | alpha-(4-Fluorophenyl)-4-(trifluoromethyl)benzenemethanol | HCID 579773 | — |
| 反応物 | 4-Chloro-2-fluorobenzaldehyde | HCID 2724908 | — |
| 生成物 | (4-Chloro-2-fluorophenyl)(4-fluorophenyl)methanol | HCID 58392437 | — |
反応手順
The title compound was prepared starting from 4.60 g (26.28 mmol) of 4-bromofluorobenzene and 5.00 g (31.53 mmol) of 4-chloro-2-fluorobenzaldehyde in analogy to the synthesis of the compound from Example 80A. 4.45 g (66% of theory) of the title compound were obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08063234B2 |
| 出典データセット | uspto-grants-2011_11 |
| ORD ID | ord-4eb600ba820a4f04a7489fc54f54436b |
| 出典メモ | uspto-grants-2011_11 |