Potassium Carbonate → HCID 22467254、化合物

HRID 561793ノート

反応式

HRID 561793 の反応式
C([C:3]1[C:8]([CH3:9])=[C:7]([Cl:10])[CH:6]=[CH:5][C:4]=1[OH:11])C.C(=O)([O-])[O-].[K+].[K+].Br[CH2:19][CH2:20][O:21][CH3:22]>CC(C)=O>[Cl:10][C:7]1[CH:6]=[CH:5][C:4]([O:11][CH2:19][CH2:20][O:21][CH3:22])=[CH:3][C:8]=1[CH3:9]

参加物

5

反応物 3

HCID 11430Potassium CarbonateHCID 809722-Bromoethyl methyl etherHCID 22134509Ethyl 4-chloro-3-methylphenol

生成物 1

HCID 22467254HCID 22467254、化合物

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

To a solution of ethyl 4-chloro-3-methylphenol (1 eq.) in acetone (0.2 M) was added potassium carbonate (5 eq.) and 1-bromo-2-methoxyethane (1.3 eq.). The resulting suspension was refluxed for 25 h. The insolubles were removed via filtration and the filtrate was concentrated in vacuo to furnish the title compound.

後処理

  1. temperatureThe resulting suspension was refluxed for 25 h
  2. customThe insolubles were removed via filtration
  3. concentrationthe filtrate was concentrated in vacuo

出典と根拠

ORDレコード
ord-224af951c7104183870510e77339fa69
出典データセット
uspto-grants-2011_11
特許番号
US08063105B2

反応ノート

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