N,N,3-trimethyl-4-nitrobenzamide → 4-amino-N,N,3-trimethylbenzamide

HRID 562508

反応式

HRID 562508 の反応式
[CH3:1][N:2]([CH3:15])[C:3](=[O:14])[C:4]1[CH:9]=[CH:8][C:7]([N+:10]([O-])=O)=[C:6]([CH3:13])[CH:5]=1>CO>[NH2:10][C:7]1[CH:8]=[CH:9][C:4]([C:3]([N:2]([CH3:15])[CH3:1])=[O:14])=[CH:5][C:6]=1[CH3:13]

参加物

3

反応物 1

HCID 786992N,N,3-trimethyl-4-nitrobenzamide

生成物 1

HCID 167817704-amino-N,N,3-trimethylbenzamide

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

N,N,3-trimethyl-4-nitrobenzamide (0.6 g, 2.88 mmol) in methanol was hydrogenated using the H-cube apparatus (1.2 mL/min, RT, atmospheric pressure). After 45 minutes the reaction was complete. Removal of the solvent in vacuo gave 4-amino-N,N,3-trimethylbenzamide as a colourless solid (quantitative); MS (ES+) 179.

後処理

  1. customthe H-cube apparatus (1.2 mL/min, RT, atmospheric pressure)
  2. customRemoval of the solvent in vacuo

出典と根拠

ORDレコード
ord-d22c9a6b44974ca3aff721ada566f115
出典データセット
uspto-grants-2011_11
特許番号
US08067417B2

関連ノート

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