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2-Bromo-5-(trifluoromethyl)benzyl alcohol → (2'-Hydroxymethyl-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Bromo-5-(trifluoromethyl)benzyl alcohol | HCID 2756248 | — |
| 反応物 | Methyl 2-(4-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)phenyl)acetate | HCID 57576289 | — |
| 生成物 | (2'-Hydroxymethyl-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester | HCID 66606415 | — |
反応手順
Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: (2-bromo-5-trifluoromethyl-phenyl)-methanol and [4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid methyl ester.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08067445B2 |
| 出典データセット | uspto-grants-2011_11 |
| ORD ID | ord-f10b5cadc393441e9d4eb1c3c8a559bb |
| 出典メモ | uspto-grants-2011_11 |