Carbamic chloride, N-ethyl-N-(phenylmethyl)- → [2'-(3-Benzyl-3-ethyl-ureidomethyl)-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl]-acetic acid methyl ester

HRID 563686

反応式

HRID 563686 の反応式
[CH3:1][O:2][C:3](=[O:25])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:21])[F:20])=[CH:15][C:14]=2[CH2:23][NH2:24])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1.[CH2:26]([N:28]([CH2:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)[C:29](Cl)=[O:30])[CH3:27]>>[CH3:1][O:2][C:3](=[O:25])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:21])([F:20])[F:22])=[CH:15][C:14]=2[CH2:23][NH:24][C:29]([N:28]([CH2:32][C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[CH2:26][CH3:27])=[O:30])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1

参加物

3

反応物 2

HCID 10679448Carbamic chloride, N-ethyl-N-(phenylmethyl)-HCID 66607149(2'-Aminomethyl-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

生成物 1

HCID 66607600[2'-(3-Benzyl-3-ethyl-ureidomethyl)-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl]-acetic acid methyl ester

実験手順

Prepared according to the procedure described in Example 131, Step 2, using the following starting materials: (2′-aminomethyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester, N-ethyl-N-benzylcarbamoyl chloride.

後処理

  1. customPrepared

出典と根拠

ORDレコード
ord-482a4383681c4c388c75ed2e954bbcdf
出典データセット
uspto-grants-2011_11
特許番号
US08067445B2

関連ノート

読み込み中…