5-Bromo-2-fluorobenzaldehyde → (5-Bromo-2-fluorophenyl)methanol

関与物質

反応手順

To a solution of 5-bromo-2-fluorobenzaldehyde (1.3 g, 6.4 mmol) in MeOH (10 mL) was added sodium borohydride (0.29 g, 7.7 mmol), and the reaction was stirred at room temperature for 5 minutes. After aqueous work-up, the residue was purified by silica gel chromatography to give the title compound.

情報源と証拠