化工社化工社 化学情報印刷レポート · 研究参考用
Methyl iodide → Methyl N-methylindole-6-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl iodide | HCID 6328 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Methyl indole-6-carboxylate | HCID 639844 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | Methyl N-methylindole-6-carboxylate | HCID 639843 | 86.9% |
反応手順
The reaction was carried out in a manner similar to Reference Example 4 except for using 3.00 (17.1 mmol) of methyl 6-indolecarboxylate, 0.68 g (17.1 mmol) of 60% sodium hydroxide, 4.86 g (34.4 mmol) of methyl iodide and 60 ml of dimethylformamide. Thus 2.75 g (86.9%) of methyl 1-methyl-6-indolecarboxylate was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06169107A |
| 出典データセット | uspto-grants-2001_01 |
| ORD ID | ord-f255b6cf83d24db78da4f92e4e6da3fc |
| 出典メモ | uspto-grants-2001_01 |