4-Methoxybenzenethiol → 2-(4-Methoxy-phenylsulfanyl)-tetradecanoic acid ethyl ester

反応式

[CH2:1]([O:3][C:4](=[O:19])[CH:5](Br)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[CH3:2].[CH3:20][O:21][C:22]1[CH:27]=[CH:26][C:25]([SH:28])=[CH:24][CH:23]=1>>[CH2:1]([O:3][C:4](=[O:19])[CH:5]([S:28][C:25]1[CH:26]=[CH:27][C:22]([O:21][CH3:20])=[CH:23][CH:24]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[CH3:2]

参加物

反応物 2

HCID 127654-Methoxybenzenethiol

HCID 85791Tetradecanoic acid, 2-bromo-, ethyl ester

生成物 1

HCID 538814162-(4-Methoxy-phenylsulfanyl)-tetradecanoic acid ethyl ester収率 98%

実験手順

2-(4-Methoxy-phenylsulfanyl)-tetradecanoic acid ethyl ester was prepared according to the general method as outlined in Example 1. Starting from the corresponding ethyl -2-bromomyristate (5.0 g, 14.9 mmol) and 4-methoxythiophenol (1.9 g, 13.4 mmol), 5.0 g of the product was isolated. Yield 98%; Light yellow oil; MS: 393 (M+H)+.

出典と根拠

ORDレコード: ord-2565799a6b4b493bb253408260e54f05
出典データセット: uspto-grants-2001_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06172057B2

反応ノート

読み込み中…