化工社化工社 化学情報印刷レポート · 研究参考用
Furan-2-boronic acid → 4-(Furan-2-yl)-2,6-dimethoxyphenol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Furan-2-boronic acid | HCID 2734357 | — |
| 反応物 | 4-Bromo-2,6-dimethoxyphenol | HCID 14845876 | — |
| 生成物 | 4-(Furan-2-yl)-2,6-dimethoxyphenol | HCID 54350835 | 79% |
反応手順
4-Bromo-2,6-dimethoxyphenol (Lee, H.; et al. Tetrahedron Letters, 2004, 45, 1019) was coupled with 2-furylboronic acid according to the procedure used in the synthesis of Example 21. Purification by chromatography (20-40% EtOAc-hexanes) gave 4-(furan-2-yl)-2,6-dimethoxyphenol as a light orange solid (1.95 g, 79% yield).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09434707B2 |
| 出典データセット | uspto-grants-2016_09 |
| ORD ID | ord-5cc3d0ab1b54469587be0918e9e18936 |
| 出典メモ | uspto-grants-2016_09 |