化工社化工社 化学情報印刷レポート · 研究参考用
Piperonylamine → 6,7-dichloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Piperonylamine | HCID 2723901 | — |
| 反応物 | 6,7-dichloro-1H-indole | HCID 12272802 | — |
| 生成物 | 6,7-dichloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | HCID 18545981 | — |
反応手順
The title compound was prepared in a fashion similar to that described in Preparation 30 from 6,7-dichloroindole (1.4 g, 7.5 mmol) and 4-piperidone hydrochloride hydrate (2.3 g, 15 mmol). The product was isolated as a white solid. Yield 1.8 g (89%). mp 252-254° C. FDMS m/e=268 (M+ of free base).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06172073B2 |
| 出典データセット | uspto-grants-2001_01 |
| ORD ID | ord-23f65b723f234b96a8fd13e8ea455e78 |
| 出典メモ | uspto-grants-2001_01 |