4-(3-Phenylpropyl)piperidine → 2,3-Dihydro-2,4,6,7-tetramethyl-2-[[4-(3-phenylpropyl)-1-piperidinyl]methyl]-5-benzofuranamine

HRID 565687

反応式

HRID 565687 の反応式
Br[CH2:2][C:3]1([CH3:16])[CH2:7][C:6]2[C:8]([CH3:15])=[C:9]([NH2:14])[C:10]([CH3:13])=[C:11]([CH3:12])[C:5]=2[O:4]1.[C:17]1([CH2:23][CH2:24][CH2:25][CH:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH3:16][C:3]1([CH2:2][N:29]2[CH2:30][CH2:31][CH:26]([CH2:25][CH2:24][CH2:23][C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH2:27][CH2:28]2)[CH2:7][C:6]2[C:8]([CH3:15])=[C:9]([NH2:14])[C:10]([CH3:13])=[C:11]([CH3:12])[C:5]=2[O:4]1

参加物

3

反応物 2

HCID 876784-(3-Phenylpropyl)piperidineHCID 108505902-Bromomethyl-2,3-dihydro-2,4,6,7-tetramethyl-5-benzofuranamine

生成物 1

HCID 154858782,3-Dihydro-2,4,6,7-tetramethyl-2-[[4-(3-phenylpropyl)-1-piperidinyl]methyl]-5-benzofuranamine収率 42%

実験手順

Using 2-bromomethyl-2,3-dihydro-2,4,6,7-tetramethyl-5-benzofuranamine and 4-(3-phenylpropyl)piperidine, the procedure of Example 1 was otherwise repeated to provide the title compound.

出典と根拠

ORDレコード
ord-567fb5f684e7435ba6b787a0853b97f6
出典データセット
uspto-grants-2001_01
特許番号
US06172085B2

関連ノート

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