3-Amino-1-propanol → HCID 22111553、化合物
反応式
[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][S:7](Cl)(=[O:9])=[O:8].[CH2:11]([CH2:14][OH:15])[CH2:12][NH2:13]>>[OH:15][CH2:14][CH2:11][CH2:12][NH:13][S:7]([CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][Cl:1])(=[O:9])=[O:8]参加物
3
実験手順
The reaction was carried out in the same manner as in Preparation Example 4 except for using 5-chloropentanesulfonyl chloride (3.08 g, 15 mmol) in place of 6-chlorohexanesulfonyl chloride, and n-propanolamine (2.48 g, 33 mmol) in place of ethanolamine in Preparation Example 4, to give a by-product [N,O-bis(5-chloropetanesulfonyl)propanolamine] from a first eluted fraction in the amount of 0.64 g and N-(3-hydroxypropyl)-5-chloropentanesulfonamide from a second eluted fraction as a colorless waxy product in the amount of 2.76 g.
後処理
- customThe reaction was carried out in the same manner as in Preparation Example 4 except
- customin Preparation Example 4
出典と根拠
- ORDレコード
- ord-18f20c6e0940413a80a07591ecb3f251
- 出典データセット
- uspto-grants-2001_01
- 特許番号
- US06172228B2
反応ノート
読み込み中…