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Triethylamine → n-(4-Hydrazino-3-isobutylphenyl)-4-methylbenzenesulphonamide hydrobromide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Bromine | HCID 24408 | — |
| 反応物 | Benzenesulfonamide, 4-methyl-N-(4-nitrophenyl)- | HCID 69772 | — |
| 反応物 | HCID 178418368 | HCID 178418368 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | n-(4-Hydrazino-3-isobutylphenyl)-4-methylbenzenesulphonamide hydrobromide | HCID 22111802 | — |
反応手順
This compound is prepared according to the procedure described in step A of Preparation 2.18, from 10 g of N-(4-nitrophenyl)-4-methylbenzenesulphonamide in 100 ml of THF and 42.6 ml of a 2M solution of isobutylmagnesium chloride in ether, followed by 4.4 ml of bromine and 23.4 ml of triethylamine. 5.9 g of the expected product are obtained, m.p.=170° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06172239B2 |
| 出典データセット | uspto-grants-2001_01 |
| ORD ID | ord-32a7ae720a0443be803c1c7691394291 |
| 出典メモ | uspto-grants-2001_01 |