Diethyl benzylphosphonate → Benzylphosphonic Acid

HRID 565992

反応式

HRID 565992 の反応式
[CH2:1]([P:8](=[O:15])([O:12]CC)[O:9]CC)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CO.Cl>[CH2:1]([P:8](=[O:9])([OH:15])[OH:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 1

HCID 14122Diethyl benzylphosphonate

生成物 1

HCID 81312Benzylphosphonic Acid収率 59.2%

試薬・触媒・溶媒 2

HCID 313Hydrochloric Acid溶媒HCID 887Methanol溶媒

実験手順

A solution of diethyl benzylphosphonate (25 g) in methanol (10 ml) and concentrated hydrochloric acid (500 ml) solution was refluxed for 4 days. The mixture was cooled to room temperature, and precipitated crystal was collected by filtration to give benzylphosphonic acid (11.17 g) as colorless crystals.

後処理

  1. customprecipitated crystal
  2. filtrationwas collected by filtration

出典と根拠

ORDレコード
ord-dde78dcacfcc4ea3b3cf341bf25c2323
出典データセット
uspto-grants-2001_01
特許番号
US06172061B2

関連ノート

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