化工社化工社 化学情報印刷レポート · 研究参考用
Hydroxyamine hydrochloride → 6-Benzyloxy-2,2-dimethylchroman-4-one oxime
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 反応物 | 6-Benzyloxy-2,2-dimethylchroman-4-one | HCID 11780992 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 6-Benzyloxy-2,2-dimethylchroman-4-one oxime | HCID 86754518 | 105.1% |
反応手順
By heating 11.3 g (40 mmol) of 6-benzyloxy-2,2-dimethylchroman-4-one with 3.1 g (44 mmol) of hydroxylamine hydrochloride in 27 ml of ethanol and 27 ml of pyridine to 70° C. for 3 h, 12.5 g of product, m.p. 105-108° C., were obtained after distilling off the solvt in vac. and precipitating with water. The product was dissolved in EA, dried, concentrated and crystallized using petroleum ether; m.p. 118-120° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06177449B1 |
| 出典データセット | uspto-grants-2001_01 |
| ORD ID | ord-68c0d3342c694d63bf6284eaafb700be |
| 出典メモ | uspto-grants-2001_01 |