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2,6-Lutidine → 3,5-Dibromosalicyl 3-butenoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,6-Lutidine | HCID 7937 | — |
| 反応物 | 3,5-Dibromosalicylic acid | HCID 18464 | — |
| 反応物 | But-3-enoyl Chloride | HCID 10975427 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | 3,5-Dibromosalicyl 3-butenoate | HCID 21262206 | — |
反応手順
3,5-Dibromosalicyl 3-butenoate is prepared by reaction of an acetone solution of 3-butenoyl chloride and 3,5-dibromosalicylic acid in the presence of 2,6-lutidine. The 3-butenoate ester is isolated and purified. In a second step, the desired oxirane, 3,5-dibromosalicyl 3,4-oxabutanoate, is prepared by reaction of 3,5-dibromosalicyl 3-butenoate and 3-chloroperbenzoic acid in chloroform solution. The desired oxirane is isolated and purified.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06180598B2 |
| 出典データセット | uspto-grants-2001_01 |
| ORD ID | ord-137ef8ba307b4b909a8d6201c4b20be9 |
| 出典メモ | uspto-grants-2001_01 |