2-Amino-5-phenylphenol → HCID 22011350、化合物

反応式

[OH:1][C:2]1[CH:8]=[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:6]=[CH:5][C:3]=1[NH2:4].[Br:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[N:22]=[C:23]=[O:24]>>[OH:1][C:2]1[CH:8]=[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:6]=[CH:5][C:3]=1[NH:4][C:23]([NH:22][C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=1[Br:15])=[O:24]

参加物

反応物 2

HCID 203762-Amino-5-phenylphenol

HCID 1370972-Bromophenyl isocyanate

生成物 1

HCID 22011350HCID 22011350、化合物

実験手順

The urea was prepared from 2-hydroxy 4-phenyl aniline(0.185 g, 1 mmol) and 2-bromophenylisocyanate(0.198 g) by general Method B. It was purified by dilution of the DMF solution with methylene chloride and precipitation with hexane(215 mg, 56%). EI-MS m/z 383(M+H)+.

後処理

customIt was purified by dilution of the DMF solution with methylene chloride and precipitation with hexane(215 mg, 56%)

出典と根拠

ORDレコード: ord-9cb1f9efe7da4fa78735e046e8d8def0
出典データセット: uspto-grants-2001_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06180675B2

反応ノート

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