3-Aminosalicylic acid → (2-Bromophenyl)urea
反応式
OC1C([NH2:11])=CC=CC=1C(O)=O.[Br:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[N:19]=[C:20]=[O:21]>>[Br:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[NH:19][C:20](=[O:21])[NH2:11]参加物
3
実験手順
The urea was prepared from 2-hydroxy 3-aminobenzoic acid(300 mg, 2 mmol) and 2-bromophenylisocyanate by general Method B. It was purified by dilution of the DMF solution with methylene chloride and precipitation with hexane(0.287 g, 41%). EI-MS m/z 351 (M+H)+.
後処理
- customIt was purified by dilution of the DMF solution with methylene chloride and precipitation with hexane(0.287 g, 41%)
出典と根拠
- ORDレコード
- ord-ec694352362047799e30bf7636f76922
- 出典データセット
- uspto-grants-2001_01
- 特許番号
- US06180675B2
反応ノート
読み込み中…