2-Bromophenyl isocyanate → (2-Bromophenyl)urea

HRID 568019ノート

反応式

HRID 568019 の反応式
S1C=CC=C1S([NH:9]C1C=CC=CC=1N)(=O)=O.[Br:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[N:24]=[C:25]=[O:26]>>[Br:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[NH:24][C:25](=[O:26])[NH2:9]

参加物

3

反応物 2

HCID 1370972-Bromophenyl isocyanateHCID 2310676N-(2-aminophenyl)thiophene-2-sulfonamide

生成物 1

HCID 139386(2-Bromophenyl)urea収率 134.9%

実験手順

The urea was synthesized from 2-(2-thiophenesulfonylamino) aniline(1 mmol) and 2-bromophenylisocyanate(1 mmol) by general Method B. It was purified by dilution with methylene chloride and precipitation with hexane. Filtering afforded the desired compound(0.29 g, 64%). EI-MS m/z 450(M−H)−.

後処理

  1. customIt was purified by dilution with methylene chloride and precipitation with hexane
  2. filtrationFiltering

出典と根拠

ORDレコード
ord-e6c156b927a740b29fa14419a8857add
出典データセット
uspto-grants-2001_01
特許番号
US06180675B2

反応ノート

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