Water → 3-Chloro-2,4-dimethoxybenzaldehyde

HRID 568674ノート

反応式

HRID 568674 の反応式
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][CH:8]=[C:5]([O:6][CH3:7])[C:4]=1[Cl:11].[CH3:12][O:13]C(Cl)Cl.O>C(Cl)Cl.Cl[Ti](Cl)(Cl)Cl>[Cl:11][C:4]1[C:3]([O:2][CH3:1])=[C:10]([CH:9]=[CH:8][C:5]=1[O:6][CH3:7])[CH:12]=[O:13]

参加物

6

反応物 3

HCID 962WaterHCID 21004Methane, dichloromethoxy-HCID 130157172-Chloro-1,3-dimethoxybenzene

生成物 1

HCID 133437053-Chloro-2,4-dimethoxybenzaldehyde

試薬・触媒・溶媒 2

HCID 24193Titanium Tetrachloride触媒HCID 6344Dichloromethane溶媒

実験手順

2-chlororesorcinol dimethyl ether (3.4 g) is dissolved in 20 ml of CH2Cl2 and TiCl4 (4.3 ml) is added. To this solution is added dichloromethyl methyl ether (2.3 g). After 30 minutes the reaction mixture is poured into H2O and extracted with ether. Drying and evaporation gives 3-chloro-2,4-dimethoxybenzaldehyde, mp 107°-108° C.

後処理

  1. extractionextracted with ether
  2. customDrying
  3. customevaporation

出典と根拠

ORDレコード
ord-bb754afce9a54c8ebd5bde9bc76de249
出典データセット
uspto-grants-1988_03
特許番号
US04728662

反応ノート

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