Salicylaldehyde → 2-Undecyloxybenzaldehyde

HRID 568900

反応式

HRID 568900 の反応式
[CH:1](=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[CH2:10](Br)[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O.CCCCCC>[CH2:20]([O:4][C:3]1[CH:5]=[CH:6][CH:7]=[CH:8][C:2]=1[CH:1]=[O:9])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH3:10]

参加物

6

反応物 3

HCID 6998SalicylaldehydeHCID 11430Potassium CarbonateHCID 127441-Bromoundecane

生成物 1

HCID 156174952-Undecyloxybenzaldehyde

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide溶媒HCID 8058Hexane溶媒

反応条件

温度
100 °C

実験手順

A mixture of salicylaldehyde (10.15 moles), undecylbromide (10.3 mmoles) and potassium carbonate (11.7 mmoles) in dimethylformamide (10 ml) is heated to 100° C. for 1 hour and then is cooled. The reaction mixture is taken up in hexane and is washed with 5 percent sodium hydroxide and brine. After treatment with anhydrous magnesium sulfate and charcoal, the volatiles are removed under vacuum and the residue is purified by flash chromatography to give the desired product.

後処理

  1. temperatureis cooled
  2. washis washed with 5 percent sodium hydroxide and brine
  3. customAfter treatment with anhydrous magnesium sulfate and charcoal, the volatiles are removed under vacuum
  4. customthe residue is purified by flash chromatography

出典と根拠

ORDレコード
ord-d9caa7c1dfbc432fa3184d36e17ae606
出典データセット
uspto-grants-1988_03
特許番号
US04730005

関連ノート

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