HCID 13592259、化合物 → 3,3-Bis(azidomethyl)oxetane
反応式
O[CH2:2][C:3]([CH2:12][O:13]S(C1C=CC(C)=CC=1)(=O)=O)([CH2:8][N:9]=[N+:10]=[N-:11])[CH2:4][N:5]=[N+:6]=[N-:7]>O1CCOCC1>[N:9]([CH2:8][C:3]1([CH2:4][N:5]=[N+:6]=[N-:7])[CH2:2][O:13][CH2:12]1)=[N+:10]=[N-:11]参加物
3
反応条件
- 温度
- 60 °C
実験手順
0.1 mole of compound 9 was dissolved in 100 ml of dry dioxane. 0.15 Mole of potassium tert.-butylate was added, with exclusion of moisture. After the reaction mixture had been stirred at 60° C. for 3 hours, it was concentrated. The residue was taken up in 400 ml of ether and the mixture was washed twice with 5% strength (weight: volume) aqueous NaCl solution. The organic phase was dried and concentrated in vacuo. The uniform product was further purified by column chromatography (eluting agent: chloroform/ethyl acetate 5:1).
後処理
- concentrationit was concentrated
- washthe mixture was washed twice with 5% strength (weight: volume) aqueous NaCl solution
- customThe organic phase was dried
- concentrationconcentrated in vacuo
- customThe uniform product was further purified by column chromatography (eluting agent: chloroform/ethyl acetate 5:1)
出典と根拠
- ORDレコード
- ord-07f45846d5b846cb9500043b92616995
- 出典データセット
- uspto-grants-1988_03
- 特許番号
- US04730069
反応ノート
読み込み中…