Dimethylamine → HCID 20148413、化合物
反応式
C(O[C:4]([C:6]1[CH:7]=[C:8]2[C:16](=[CH:17][CH:18]=1)[NH:15][C:14]1[CH:13]=[N:12][CH:11]=[CH:10][C:9]2=1)=[O:5])C.[CH3:19][NH:20][CH3:21]>C=C>[CH3:19][N:20]([CH3:21])[C:4]([C:6]1[CH:7]=[C:8]2[C:16](=[CH:17][CH:18]=1)[NH:15][C:14]1[CH:13]=[N:12][CH:11]=[CH:10][C:9]2=1)=[O:5]参加物
4
実験手順
150 mg of 6-ethoxycarbonyl-β-carboline are heated in 5 ml of ethylene gylcol with 2 ml of dimethylamine solution for 20 hours to 100° C. After cooling, it is placed on ice, extracted with ethyl acetate and the organic phase is dried, filtered and concentrated. 50 mg of 6-dimethylaminocarbonyl-β-carboline are obtained as oil after chromatography on silica gel with methylene chloride/ethanol=10:1.
後処理
- temperatureAfter cooling
- extractionextracted with ethyl acetate
- customthe organic phase is dried
- filtrationfiltered
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-add9c74c1d444bdd96b0b82f2af42f84
- 出典データセット
- uspto-grants-1988_03
- 特許番号
- US04731358
反応ノート
読み込み中…