Boron, trifluoro(methanol)-, (T-4)- → Methyl 2-(3-methoxyphenyl)-5-oxo-1-phenylpyrrolidin-3-carboxylate

HRID 569238

反応式

HRID 569238 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]2[CH:13]([C:14]([OH:16])=[O:15])[CH2:12][C:11](=[O:17])[N:10]2[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:6]=[CH:7][CH:8]=1.B(F)(F)F.[CH3:28]O>>[CH3:28][O:15][C:14]([CH:13]1[CH2:12][C:11](=[O:17])[N:10]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:9]1[C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=1)=[O:16]

参加物

3

反応物 2

HCID 11062313Boron, trifluoro(methanol)-, (T-4)-HCID 133619852-(3-Methoxyphenyl)-5-oxo-1-phenylpyrrolidin-3-carboxylic acid

生成物 1

HCID 13362002Methyl 2-(3-methoxyphenyl)-5-oxo-1-phenylpyrrolidin-3-carboxylate

実験手順

A solution of 25.0 gm. of 2-(3-methoxyphenyl)-5-oxo-1-phenylpyrrolidin-3-carboxylic acid in 200 ml 10-15% boron fluoride-methanol was refluxed for 8 hours and upon following the workup for example 1C the product was obtained as an oil.

後処理

  1. customwas obtained as an oil

出典と根拠

ORDレコード
ord-999296dc3304461a8deb656b3ad85617
出典データセット
uspto-grants-1988_03
特許番号
US04731457

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