Malonic Acid → HCID 54430904、化合物

関与物質

反応手順

Reaction of 3-(1-tridecynyl)furan-2-carboxaldehyde (700 mg, 2.56 mmole from Example 6) with malonic acid (535 mg, 5.12 mmole) as described in Example 2 gave 0.778 g (98%) of the title compound, mp (methanol) 71°-72° C. νmax (mull) 3140, 2600 (broad), 1680, 1630, 1465 cm-1 ; δ(DMSO) 0.80 (3H, distorted t, terminal CH3), 1.09-1.60 (18H, m, alkylene chain), 2.42 (2H, t, CH2C≡C), 6.25 (1H, d, J 15.3 Hz, C=CH--CO2H), 6.62 (1H, d, J 2 Hz, C-4H), 7.33 (1H, d, J 15.3 Hz, Ar CH=C), 7.79 (1H, d, J 2 Hz, C-5H).

情報源と証拠