2-(Trifluoromethyl)acrylic acid → 3-Acetylthio-2-trifluoromethylpropanoic acid

HRID 569861

反応式

HRID 569861 の反応式
[C:1]([OH:6])(=[S:5])[CH:2](C)O.[F:7][C:8]([F:15])([F:14])[C:9](=[CH2:13])[C:10]([OH:12])=[O:11]>>[C:1]([S:5][CH2:13][CH:9]([C:8]([F:15])([F:14])[F:7])[C:10]([OH:12])=[O:11])(=[O:6])[CH3:2]

参加物

3

反応物 2

HCID 5876942-(Trifluoromethyl)acrylic acidHCID 178473673HCID 178473673、化合物

生成物 1

HCID 128330143-Acetylthio-2-trifluoromethylpropanoic acid

実験手順

A mixture of thiolactic acid (50 g.) and 2-(trifluoromethyl)acrylic acid [M. W. Buxton, et al., J. Chem. Soc., 366 (1954)] (66 g.) is heated on the steam bath for one hour and then stored at room temperature for eighteen hours. The reaction mixture is distilled in vacuo to give 3-acetylthio-2-trifluoromethylpropanoic acid.

後処理

  1. temperatureis heated on the steam bath for one hour
  2. waitstored at room temperature for eighteen hours
  3. distillationThe reaction mixture is distilled in vacuo

出典と根拠

ORDレコード
ord-f1430a46860347daae74740f3bca9852
出典データセット
uspto-grants-1988_03
特許番号
US04734420

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