Dimethylformamide dimethyl acetal → HCID 54034117、化合物
反応式
[CH3:1][N:2]1[C:6]2[CH2:7][CH2:8][CH2:9][C:10](=[O:12])[CH2:11][C:5]=2[CH:4]=[N:3]1.CO[CH:15](OC)[N:16]([CH3:18])[CH3:17]>>[CH3:15][N:16]([CH:18]=[C:11]1[C:5]2[CH:4]=[N:3][N:2]([CH3:1])[C:6]=2[CH2:7][CH2:8][CH2:9][C:10]1=[O:12])[CH3:17]参加物
3
実験手順
A mixture of 27.6 g of 4,6,7,8-tetrahydro-1-methyl-5(1H)-cycloheptapyrazolone and 100 ml of N,N-dimethylformamide dimethyl acetal was heated at reflux for 1.5 hours. The solvent was then removed under reduced pressure and the residue was flash chromatographed (10% methanol in dichloromethane) to give 4-(dimethylaminomethylene)-4,6,7,8-tetrahydro-1-methyl-5(1H)-cycloheptapyrazolone.
後処理
- temperaturewas heated
- temperatureat reflux for 1.5 hours
- customThe solvent was then removed under reduced pressure
- customchromatographed (10% methanol in dichloromethane)
出典と根拠
- ORDレコード
- ord-d4fa3f25531f4d0180b591339bf6ce33
- 出典データセット
- uspto-grants-1988_03
- 特許番号
- US04734429
反応ノート
読み込み中…