Hydrazine → HCID 178434195、化合物

HRID 569903

反応式

HRID 569903 の反応式
[C:1]([CH:4]1[C:9](=[O:10])[CH2:8][CH2:7][CH2:6][C:5]1=O)(=O)[CH3:2].[NH2:12][NH2:13]>CO>[CH3:2][C:1]1[C:4]2[C:9](=[O:10])[CH2:8][CH2:7][CH2:6][C:5]=2[NH:13][N:12]=1

参加物

4

反応物 2

HCID 9321HydrazineHCID 1381042-Acetyl-1,3-cyclohexanedione

生成物 1

HCID 178434195HCID 178434195、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒2 回

実験手順

To an ice-cold solution of 33.3 grams of 2-acetyl-1,3-cyclohexanedione in 400 ml of methanol was added dropwise a solution of 7.2 ml of hydrazine in 50 ml of methanol and the resulting reaction mixture was heated at reflux for 20 hours. The solvent was then removed under reduced pressure and the residue was triturated in ethyl ether to give 1,5,6,7-tetrahydro-3-methyl-4H-indazol-4-one as a yellow crystalline solid melting at about 154°-157° C.

後処理

  1. customthe resulting reaction mixture
  2. temperaturewas heated
  3. temperatureat reflux for 20 hours
  4. customThe solvent was then removed under reduced pressure
  5. customthe residue was triturated in ethyl ether

出典と根拠

ORDレコード
ord-494d869e6cbc42cf8d34d3dae1d77716
出典データセット
uspto-grants-1988_03
特許番号
US04734430

関連ノート

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