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HRID 570081作成日:2026年10月27日

Methylphenidate Hydrochloride → Methylphenidate

https://huagongshe.com/reaction/570081

反応式

関与物質

役割名称HCID仕込み量
反応物Methylphenidate HydrochlorideHCID 9280—
溶媒WaterHCID 962—
生成物MethylphenidateHCID 4158—

反応手順

In a preferred manufacturing process, methylphenidate HCl and microcrystalline cellulose (Avicel PH-101) are blended in a Hobart Mixer. Purified water is added to the dry mixture and the wet granulation is extruded (MG-55 Multi granulator). The extrudate is then spheronized into pellets (Caleva Model# SPH250). The wet pellets are dried (Fluid Air Model#0050) and sieved (30 mesh<Acceptable<20 mesh).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09023389B1
出典データセットuspto-grants-2015_05
ORD IDord-f043726f75b34528a960030d69294740
出典メモuspto-grants-2015_05