Triethyl phosphite → HCID 12565589、化合物

反応式

Br[CH:2]([CH2:7][CH3:8])[C:3]([O:5][CH3:6])=[O:4].[CH2:9]([O:11][P:12]([O:16]CC)[O:13][CH2:14][CH3:15])[CH3:10]>>[CH3:6][O:5][C:3](=[O:4])[CH:2]([P:12]([O:13][CH2:14][CH3:15])([O:11][CH2:9][CH3:10])=[O:16])[CH2:7][CH3:8]

参加物

反応物 2

HCID 31215Triethyl phosphite

HCID 95577Butanoic acid, 2-bromo-, methyl ester

生成物 1

HCID 12565589HCID 12565589、化合物

反応条件

温度: 110 °C

実験手順

Methyl 2-bromobutanoate (92 g, 0.508 mol) and triethylphosphite (95 g, 0.57 mol) were mixed, and the mixture was stirred at 110° C. for 3 days. The reaction mixture was dried under reduced pressure to give the title compound.

後処理

customThe reaction mixture was dried under reduced pressure

出典と根拠

ORDレコード: ord-6957fe9e5e124753bb9629e732d1a61f
出典データセット: uspto-grants-2015_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09024044B2

反応ノート

読み込み中…

参加物