Acenaphthenequinone → 7,9-Diphenyl-8H-cyclopenta[a]acenaphthylen-8-one

HRID 571586

反応式

HRID 571586 の反応式
[C:1]1(=O)[C:11]2=[C:12]3[C:7](=[CH:8][CH:9]=[CH:10]2)[CH:6]=[CH:5][CH:4]=[C:3]3[C:2]1=O.[C:15]1([CH2:21][C:22](=[O:30])[CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.[OH-].[K+]>C(O)C>[C:24]1([C:23]2[C:22](=[O:30])[C:21]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[C:2]3[C:3]4=[C:12]5[C:7](=[CH:6][CH:5]=[CH:4]4)[CH:8]=[CH:9][CH:10]=[C:11]5[C:1]=23)[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1

参加物

5

反応物 3

HCID 6724AcenaphthenequinoneHCID 75931,3-Diphenyl-2-propanoneHCID 14797Potassium Hydroxide2 回

生成物 1

HCID 2671457,9-Diphenyl-8H-cyclopenta[a]acenaphthylen-8-one収率 71.3%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒3 回

実験手順

An amount of 5.9 g (32.4 mmol) of acenaphthenequinone and 7.5 g (35.7 mmol) of 1,3-diphenyl-2-propanone were suspended in 150 ml of ethanol and a solution of 2 g of potassium hydroxide in ethanol was added. After the mixture was heated to the reflux temperature, the same amount of the solution of potassium hydroxide in ethanol was further added and allowed to react for five minutes. The solid substance deposited after cooled on ice was filtered and washed with ethanol to obtain 8.24 g (23.1 mmol) of 7,9-diphenylcyclopenta[a]acenaphthylene-8-one. The yield was 71.3%.

後処理

  1. temperatureAfter the mixture was heated to the reflux temperature
  2. customto react for five minutes
  3. temperatureThe solid substance deposited after cooled on ice
  4. filtrationwas filtered
  5. washwashed with ethanol

出典と根拠

ORDレコード
ord-67ff0ccdf2d04779ba9e16d21b7f7d1e
出典データセット
uspto-grants-2015_05
特許番号
US09028976B2

関連ノート

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