3-(Trifluoromethyl)aniline → 3-(2-Chloroethyl)-1-[3-(trifluoromethyl)phenyl]urea
反応式
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:4]=[C:5]([NH2:9])[CH:6]=[CH:7][CH:8]=1.[Cl:12][CH2:13][CH2:14][N:15]=[C:16]=[O:17]>C1(C)C=CC=CC=1>[Cl:12][CH2:13][CH2:14][NH:15][C:16]([NH:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:10])([F:11])[F:1])[CH:4]=1)=[O:17]参加物
4
実験手順
Using analogous reagents and reaction conditions as described in Example 1 above, 3-trifluoromethyl-phenylamine (2.0 g, 12.412 mmol) in toluene (20 mL) was reacted with 1-chloro-2-isocyanatoethane (1.96 g, 18.618 mmol to give 3.2 g of pure product (96%)
後処理
- customreagents and reaction conditions
出典と根拠
- ORDレコード
- ord-57c089001175415c92bcf0bd1c1b4a05
- 出典データセット
- uspto-grants-2015_05
- 特許番号
- US09029399B2
反応ノート
読み込み中…