Hydrochloric Acid → 2-(3-Octadecyloxy-2,2-bis-octadecyloxymethyl-propoxy)-9-fluorenone

HRID 573031

反応式

HRID 573031 の反応式
I[CH2:2][C:3]([CH2:44][O:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][CH2:60][CH2:61][CH2:62][CH3:63])([CH2:24][O:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH3:43])[CH2:4][O:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23].[OH:64][C:65]1[CH:77]=[CH:76][C:75]2[C:74]3[C:69](=[CH:70][CH:71]=[CH:72][CH:73]=3)[C:68](=[O:78])[C:67]=2[CH:66]=1.C(=O)([O-])[O-].[K+].[K+].Cl>CN(C=O)C>[CH2:46]([O:45][CH2:44][C:3]([CH2:4][O:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])([CH2:24][O:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH3:43])[CH2:2][O:64][C:65]1[CH:77]=[CH:76][C:75]2[C:74]3[C:69](=[CH:70][CH:71]=[CH:72][CH:73]=3)[C:68](=[O:78])[C:67]=2[CH:66]=1)[CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][CH2:60][CH2:61][CH2:62][CH3:63]

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 11430Potassium CarbonateHCID 813862-Hydroxyfluoren-9-oneHCID 594992271-[3-Iodo-2,2-bis(octadecyloxymethyl)propoxy]octadecane

生成物 1

HCID 594992402-(3-Octadecyloxy-2,2-bis-octadecyloxymethyl-propoxy)-9-fluorenone収率 92.2%

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

反応条件

温度
130 °C

実験手順

1-(3-Iodo-2,2-bis-octadecanoxymethyl-propoxy)octadecane (500 mg, 102 μmol) and 2-hydroxy-9-fluorenone (30 mg, 152 μmol) were dissolved in DMF (2 ml), potassium carbonate (21 mg, 152 μmol) was added, and the mixture was stirred at 130° C. After completion of the reaction, 0.5N hydrochloric acid (6 ml) was added, the precipitate was filtered, and the precipitate was washed with acetonitrile and water to give 2-(3-octadecyloxy-2,2-bis-octadecyloxymethyl-propoxy)-9-fluorenone (101 mg, 94 μmol).

後処理

  1. additionwas added
  2. filtrationthe precipitate was filtered
  3. washthe precipitate was washed with acetonitrile and water

出典と根拠

ORDレコード
ord-a664fb3804fe417eb2cf1da3e9a7e335
出典データセット
uspto-grants-2015_05
特許番号
US09029504B2

関連ノート

読み込み中…