化工社化工社 化学情報印刷レポート · 研究参考用
2-methyl-1H-indol-5-ol → 2-(2-Amino-pyridin-4-yloxy)-4-fluoro-benzoic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-methyl-1H-indol-5-ol | HCID 83336 | — |
| 反応物 | Benzoic acid, 2,4-difluoro-, ethyl ester | HCID 2737170 | — |
| 反応物 | HCID 178507942 | HCID 178507942 | — |
| 生成物 | 2-(2-Amino-pyridin-4-yloxy)-4-fluoro-benzoic acid methyl ester | HCID 67227884 | — |
反応手順
The title compound was prepared by substituting methyl 2,4-difluorobenzoate for ethyl 2,4-difluorobenzoate and 2-aminopyridin-4-ol for 2-methyl-5-indolol in EXAMPLE 3A, except here heating was at 130° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09029404B2 |
| 出典データセット | uspto-grants-2015_05 |
| ORD ID | ord-3b599d003da043559b397b090ff61417 |
| 出典メモ | uspto-grants-2015_05 |