化工社化工社 化学情報印刷レポート · 研究参考用
Methyl iodide → HCID 178503348、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl iodide | HCID 6328 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | HCID 178527819 | HCID 178527819 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | HCID 178503348 | HCID 178503348 | 22% |
反応手順
To a solution of 1H-imidazo[4,5-b]pyridine-2-thiol (5.0 g) in acetone (75 mL) were added MeI (2.3 mL) and K2CO3 (18 g) at room temperature. After stirring for 1 day, the mixture was filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (AcOEt/hexane) to give the title compound (1.2 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09029536B2 |
| 出典データセット | uspto-grants-2015_05 |
| ORD ID | ord-83f8525bd2344d57981d3734115d833a |
| 出典メモ | uspto-grants-2015_05 |