2-Iodobenzylic alcohol → 2-Iodobenzaldehyde

HRID 573469

反応式

HRID 573469 の反応式
[I:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][OH:5]>ClCCl.[O-2].[Mn+2]>[I:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[O:5]

参加物

4

反応物 1

HCID 1076292-Iodobenzylic alcohol

生成物 1

HCID 6434392-Iodobenzaldehyde収率 91%

試薬・触媒・溶媒 2

HCID 160959Manganese oxide触媒HCID 6344Dichloromethane溶媒

実験手順

In a flask, 2-iodobenzyl alcohol (4 g, 17.09 mmol) was dissolved in dichloromethane (MC, 85 ml), and then, manganese oxide (MnO2, 14.86 g, 170.92 mmol) was added thereto. The obtained reaction product was stirred under the reflux condition. When the reaction was completed, the obtained reaction product was cooled to the room temperature, and then, fiteated and concentrated using celite, to obtain the title compound (3.6 g, yield 91%).

後処理

  1. customThe obtained reaction product
  2. customthe obtained reaction product
  3. concentrationfiteated and concentrated

出典と根拠

ORDレコード
ord-4e7787d867b241b6965a32d5b6f0e10d
出典データセット
uspto-grants-2015_05
特許番号
US09029589B2

関連ノート

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