化工社化工社 化学情報印刷レポート · 研究参考用
3-Aminophenol → 5-Hydroxy-2-(3-hydroxyphenyl)isoindoline-1,3-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Aminophenol | HCID 11568 | — |
| 反応物 | 4-Hydroxyphthalic acid | HCID 11881 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 5-Hydroxy-2-(3-hydroxyphenyl)isoindoline-1,3-dione | HCID 19793984 | 80.5% |
反応手順
m-Aminophenol(13.23 g, 0.12 mol) and 4-hydroxyphthalic acid (16.98 g, 0.09 mol) are allowed to react in refluxing acetic acid as described above. The product (21.6 g, 91%), collected as a tan solid, is recrystallized from methanol to give 18.5 g of pale yellow powder [mp 270° C. differential scanning calorimetry] having the following structure: ##STR7##
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05246751 |
| 出典データセット | uspto-grants-1993_09 |
| ORD ID | ord-bae6517f0d0c4e2b88dc16d1d8fd4fb6 |
| 出典メモ | uspto-grants-1993_09 |