(R)-tert-butyl 3-ureidopyrrolidine-1-carboxylate → (R)-1-(pyrrolidin-3-yl)urea
反応式
[NH:1]([C@@H:5]1[CH2:9][CH2:8][N:7](C(OC(C)(C)C)=O)[CH2:6]1)[C:2]([NH2:4])=[O:3]>Cl>[NH:7]1[CH2:8][CH2:9][C@@H:5]([NH:1][C:2]([NH2:4])=[O:3])[CH2:6]1参加物
3
実験手順
(R)-tert-butyl 3-ureidopyrrolidine-1-carboxylate from step A was treated with HCl solution (in EtOAc, 30 mL) for 2 hours. The mixture was concentrated in vacuo to give the crude title compound. MS (m/z): 130 (M+H)+.
後処理
- concentrationThe mixture was concentrated in vacuo
出典と根拠
- ORDレコード
- ord-3adef84ce87b4695bba69b0c8b6f8979
- 出典データセット
- uspto-grants-2016_09
- 特許番号
- US09434726B2
反応ノート
読み込み中…